Antibacterial drugs
December 7, 2017Antiprotozoal drugs
December 10, 2017Drugs for threadworms
Anthelmintics are effective in threadworm infections, but their use needs to be combined with hygienic measures to break the cycle of auto-infection. All members of the family require treatment.
MEBENDAZOLE:
Indications: Ancylostoma Duodenale Infection, Ascariasis, Enterobiasis, Necator Americanus Infection, Trichuriasis (threadworm, roundworm, whipworm, and hookworm infections).
Contraindications: Disease of Liver.
Dose and Administration: Threadworms, adult and child over 2 years, 100 mg as a single dose; if reinfection occurs second dose may be needed after 2 weeks. Whipworms, adult and child over 2 years, 100 mg twice daily for 3 days.
Drugs for hookworms
ALBENDAZOLE:
Indications: Echinococcus Granulosus Infection, Echinococcus Granulosus Infection of the Liver, Echinococcus Granulosus Infection of the Lung, and Echinococcus Granulosus Infection of the Peritoneum, Neurocysticercosis.
Contraindications: Disease of Liver, Anemia, and Neutropenic Disorder.
Dose and Administration: 400 mg by oral route as single dose with food.
Schistosomicides
PRAZIQUANTEL:
Indications: Clonorchiasis due to C. Sinensis, Opisthorchiasis, Schistosomiasis, Schistosomiasis due to S. Haematobium, Schistosomiasis due to S. Japonicum, Schistosomiasis due to S. Mansoni, Schistosomiasis due to S. Mekongi. Contraindications: Ocular Cysticercosis.
Dose and Administration: 25 mg/kg by oral route 3 times per day for 1 day doses not being less than 4 hours and not more than 6 hours apart.
