Drugs for threadworms
Anthelmintics are effective in threadworm infections, but their use needs to be combined with hygienic measures to break the cycle of auto-infection. All members of the family require treatment.
MEBENDAZOLE:
Indications: Ancylostoma Duodenale Infection, Ascariasis, Enterobiasis, Necator Americanus Infection, Trichuriasis (threadworm, roundworm, whipworm, and hookworm infections).
Contraindications: Disease of Liver.
Dose and Administration: Threadworms, adult and child over 2 years, 100 mg as a single dose; if reinfection occurs second dose may be needed after 2 weeks. Whipworms, adult and child over 2 years, 100 mg twice daily for 3 days.
Drugs for hookworms
ALBENDAZOLE:
Indications: Echinococcus Granulosus Infection, Echinococcus Granulosus Infection of the Liver, Echinococcus Granulosus Infection of the Lung, and Echinococcus Granulosus Infection of the Peritoneum, Neurocysticercosis.
Contraindications: Disease of Liver, Anemia, and Neutropenic Disorder.
Dose and Administration: 400 mg by oral route as single dose with food.
Schistosomicides
PRAZIQUANTEL:
Indications: Clonorchiasis due to C. Sinensis, Opisthorchiasis, Schistosomiasis, Schistosomiasis due to S. Haematobium, Schistosomiasis due to S. Japonicum, Schistosomiasis due to S. Mansoni, Schistosomiasis due to S. Mekongi. Contraindications: Ocular Cysticercosis.
Dose and Administration: 25 mg/kg by oral route 3 times per day for 1 day doses not being less than 4 hours and not more than 6 hours apart.
