AMIODARONE SUSPENSION 40MG/ML
Generic Name : Amiodarone
Indication : Arrhythmias
Dosage Form : Suspension
Strength : 40mg/mL
Stability : 28 days
Storage : Room temperature and protect from light
INGREDIENTS:
Amiodarone 200mg 20 tablets
Sodium Bicarbonate – ~10mL
Vehicle qs 100mL
How to prepare AMIODARONE SUSPENSION 40MG/ML:
1. Measure out the vehicle and adjust the pH to pH 6-7 using Sodium Bicarbonate 5% solution.
2. Grind the tablets to fine powder in a mortar and levigate the powder using a small amount of vehicle (pH adjusted) to form smooth paste.
3. Gradually add the vehicle (pH adjusted) in small amounts to the paste, mix well until liquid is formed and transfer into a container.
4. Use additional vehicle to rinse the remaining drug from the mortar and add to the container.
5. Make up the final volume using more vehicle (pH adjusted) and stir well.
6. Shake well and label.
NOTES:
1. Shake the bottle before consume.
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