PROPRANOLOL SUSPENSION 1MG/ML
Generic Name : Propranolol
Indication : Dysrhythmias, tachycardia, hypertrophic obstructive cardiomyopathy (For cardiologist only)
Dosage Form : Suspension
Strength : 1mg/mL
Stability : 45 days
Storage : Refrigerate and protect from light
INGREDIENTS:
Propranolol 40mg 6 tablets
Distilled Water (wetting agent) – 4.8mL
Citric Acid Solution 25% 1mL
Simple Syrup qs 240mL
How to prepare PROPRANOLOL SUSPENSION 1MG/ML:
1. Crush tablets in a mortar to fine powder.
2. Levigate the powder with distilled water until smooth.
3. Add a small amount of simple syrup to form smooth paste. Add more syrup until liquid is formed and transfer the contents into a graduated cylinder. Use additional simple syrup to rinse the remaining drug from the mortar.
4. Add citric acid to the suspension in the graduate. Mix well.
5. Make up to final volume with simple syrup.
6. Transfer the suspension into an amber bottle.
7. Shake well and label.
NOTE:
1. Keep in an amber glass bottle.
2. Citric acid is used only for pH adjustment. No need to decrease expiry to citric acid’s expiry.